Description
Doctor's Best Hyaluronic Acid with Chondroitin Sulfate
- Science-based nutrition
- Dietary supplement
- Supports healthy joints*
- Supports youthful skin*
Best Hyaluronic Acid wth Chondroitin Sulfate contains patented BioCell Collagen II® (US patents 6,025,327; 6,323,319; & 6,780,841). BioCell Collagen II® is sourced from chicken sternal cartilage and provides bioavailable, low molecular weight hyaluronic acid. It is standardized to contain 10% Hyaluronic Acid, 20% Chondroitin Sulfate, and 60% Collagen Type II.
Hyaluronic Acid and Collagen are vital structural components of the skin that decline as we age, and are partly responsible for the skin's moisture, suppleness and elasticity. BioCell Collagen II® contains key components that can help support healthy skin and joint function*.
Suggested Adult Use: Take 1 tablet daily, or as directed by a health care practitioner. Take with 8-10 ounces of water, with or without food.
Other Ingredients: Calcium phosphate, cellulose, stearic acid, magnesium stearate (vegetable source), modified cellulose gum, silicon dioxide.
Contains nothing other than listed ingredients.
BioCell Collagen II is hydrolyzed and denatured to low molecular weight compounds that increase the bioavailability and absorption of its components. Undenatured products have a lower absorption rate due to their larger molecule size. Hyaluronic Acid and Collagen are vital structural components of skin that decline as we age, influencing our skin’s moisture, suppleness, and elasticity. BioCell Collagen II can help replenish the body’s natural supply of these components, which in turn can support healthy skin and joint function.
Supports Healthy Joint Structure and Function*
Components of BioCell Collagen II® including collagen type II, chondroitin sulfate, and hyaluronic acid (HA) can enhance the normal production of proteoglycans in the joint matrix, thereby enhancing support for healthy joint function and maintaining joint shock absorption and cushioning.
Chondroitin Sulfate
Chondroitin has been well studied for its effects on joint health. In a double-blind trial consisting of 146 volunteers, chondroitin sulfate was administered daily for 6 months and changes in joint function were measured according to several clinical parameters. Significant improvements in joint health were noted after the first month and they were maintained for three months after the subjects stopped taking the chondroitin sulfate.1 In another double-blind study, 192 subjects took either chondroitin sulfate or placebo daily for one year. At the end of the trial, subjects who had taken chondroitin sulfate displayed better joint function and maintenance of healthy joint cartilage thickness than subjects placed on the placebo. The researchers reported that chondroitin clearly enhances the body’s ability to maintain normal joint structure and function.2
Collagen Type II
The benefits of collagen type II in supporting healthy joint and skin function have been extensively researched in both animal and clinical studies. A randomized controlled trial conducted on 60 volunteers found that oral administration of chicken collagen type II for 3 months led to a significant increase in healthy joint structure, as compared to no measurable improvement in the placebo group.3 In another double-blind, placebo-controlled trial, 274 individuals were given collagen type II orally for 24 weeks. The supplement was shown to support healthy joint function, and no adverse effects were observed during this comprehensive clinical trial.4 Other studies have shown that hydrolyzed collagen provides a substantial advantage in bioavailability over non-hydrolyzed collagen, thereby having the potential to enhance healthy joint structure more efficiently.5
Hyaluronic Acid (HA)
Hyaluronic Acid (HA) is a type of building block called a glycosaminoglycan that plays an important role in supporting the structural strength of connective tissue and cartilage. Healthy connective tissue and cartilage maintenance is critical for normal skin and joint function. HA is found in a high concentration in the synovial fluid, where it serves to enhance joint lubrication and the elastic structural and functional characteristics of the joint. A clinical study in 2007 with 98 participants determined that a healthy concentration of HA in synovial fluid is a strong indicator of joint health.6 Since the body’s supply of HA naturally decreases with age, Best Hyaluronic Acid with Chondroitin Sulfate was formulated to help maintain healthy HA levels, allowing for the extended maintenance of joint and skin.
In another interesting double-blind clinical study, researchers found that the group consuming HA displayed not only superior joint function, but also a detectable decrease in clicking sounds produced by the joints. These results were observed at 1 month (90% of subjects experienced benefits) and 6 months (63% still benefited), compared to about 26% of the placebo group at 6 months. 7
Helps Maintain Youthful Skin*
HA also plays an important role in maintaining the health and natural beauty of the skin. The compound enhances the structure and volume of the skin by promoting healthy connective tissues that interact with the skin. HA plays a direct role in the attraction and maintenance of moisture in the skin. As HA concentrations naturally decrease in the elderly, it may become difficult for the skin to retain moisture, leaving the skin dry and uncomfortable.8 Researchers have performed comparative measurements of hyaluronic acid levels in the skin of young and elderly individuals. Results indicate that there is a normal and progressive reduction in the number of hyaluronic acid granules in human skin with age—so much of a reduction, in fact, that a complete absence of these granules was seen in healthy individuals 60 years or older. These variations in HA levels with age may account for the decreased turgidity, wrinkled appearance, and altered elasticity of skin tissue.9 Recent in-vitro laboratory studies are now indicating that HA not only provides moisture retention and structural support to the skin, but also promotes cellular vitality. The results of one such study indicate that HA given to human epidermal (skin) cells induces cell signaling that promotes natural cell repair and tissue renewal.10
The BioCell Collagen II® in Best Hyaluronic Acid with Chondroitin Sulfate provides a safe, natural, standardized source of building blocks useful for maintaining joint structure and function, as well as promoting the integrity of healthy skin.
